JUUL Side Effects: What Are the Health Risks? Vaping Possible Negative Effects on Lungs: State of the Art From Lung Capacity Alteration to Cancer Cureus The rise of teen vaping is worrying doctors worldwide. While e cigarettes were once marketed as a safer alternative, research shows they contain nicotine, heavy metals, and cancer causing chemicals that can damage developing Thirdhand Vapor from E cigarettes Damages the Lungs of Mice Thirdhand Smoke Resource Center Can Vaping Cause Lung Cancer? Here's What We Know. Vaping can have serious negative impacts on both your lungs and your overall health. Here are the potential risks that we already know about, even if the vape is nicotine free: